Removing morphine tolerance could eliminate the need for increasing doses of painkillers to treat chronic pain. In some cases, patients develop a tolerance so high, the medication stops working altogether. In the study, imatinib not only prevented morphine tolerance but reversed tolerance in rats that received high morphine doses continuously for several days.
Related Articles on Pain Management:
CDC Report Suggests Use of Antidote Could Have Prevented Opioid Overdose Deaths
American Academy of Pain Medicine: Eliminate Pain as a Major Health Crisis Now
USA Pain Professionals Opens in New Mexico
Study: Reformulated Imatinib Eliminates Morphine ToleranceWritten by Abby Callard | February 20, 2012
Researchers at the University of Texas MD Anderson Cancer Center have eliminated morphine tolerance in rats by reformulating the common cancer drug imatinib, according to a news release.
© Copyright ASC COMMUNICATIONS 2011. Interested in LINKING to or REPRINTING this content? View our policies here.