6 Findings on High-Dose BMP for Spine Surgery

Spine

A study published in the Journal of Bone and Joint Surgery examined the impact of high-dose rhBMP-2.

The study authors examined 502 consecutive adult patients who received a high dosage, on average 115 mg, of rhBMP-2, for complex spinal procedures. There were 265 primary and 237 revision procedures with 261 patients receiving an interbody device. There was an average of 11.5 vertebrae instrumented.

 

The researchers found:

 

•    Interoperative complication rate of 8.2 percent
•    Major medical perioperative complication rate of 11.6 percent
•    Major perioperative surgical complication rate of 11.6 percent
•    Minor medical complication rate of 18.9 percent
•    Minor surgical complication rate of 2.6 percent.
•    Cancer prevalence of 3.4 percent but no correlation between increasing rhBMP-2 dosage and cancer, radiculopathy or seroma.

 

More Articles on Spine Surgeons:
8 Strategies for Better Spine Surgeon Documentation—And Why It's Necessary to Improve
7 Access to Care Issues for Spine Patients & How Surgeons Can Overcome Them
10 Key Components of On-Call Contracts for Spine Surgeons

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