Symmetry Medical has announced the launch of 12 new line enhancements to the BOOKWALTER Retractor System.

Belgrade, Mont.-based medical device company Bacterin reported net income loss of more than $2 million during the fourth quarter of 2011, and a loss of more than $16 million in 2011.

Integra LifeScience announced the first implantation of its PyroTITAN Humeral Resurfacing Implant for shoulder resurfacing.

Here are 15 of the most profitable orthopedics- and spine-focused medical device companies in 2011 based on financial reports. Companies that report based on the fiscal were reported as first and second quarters of the 2012 fiscal year and third and fourth quarters of the 2011 fiscal year for an accurate comparison. For companies with primary business lines outside of orthopedics and spine, we focused on the sales and revenue generated by the orthopedics and spine business lines only. Information was not available for all orthopedic and spine device companies. For questions or comments, contact Laura at This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

Generic orthopedic device pioneer Emerge Medical has signed a nationwide agreement with Premier healthcare alliance to provide the company's devices to Premier hospital members.

MiMedx Group announced it signed a global distribution agreement with Systagenix.

Smith & Nephew has sued Triad Group of Hartland for $3.2 million in lost inventory after both companies voluntarily recalled their alcohol wipes and swabs in January 2011, according to a Milwaukee Journal Sentinel report.

Exactech announced that the Deferred Prosecution Agreement, effective since in December 2010, has expired.

Sanuwave Health reported $802,572 in revenue for 2011, a 10 percent increase over 2010.

Internal Fixation Systems announced the launch of its Large Cannulated Screw System and Temporary External Fixator System.