The global spinal biologics market is expected to reach $2.4 billion by 2020, according to a MarketsandMarkets report. Here are eight companies leading the spinal biologics field.
1. Medtronic (Minneapolis). Medtronic is a medical device manufacturer operating in more than 160 countries with more than 360 locations worldwide. The Memphis, Tenn.-based Spinal and Biologics Business at Medtronic is the company's second-largest business.
2. DePuy Synthes (Raynham, Mass.). DePuy Synthes Spine's biomaterials offerings include ViviGen Cellular Bone Matrix, which can be used as an alternative to autograft, the chronOS Bone Graft Substitute for use in posterolateral spinal fusion, Conform Demineralized Cancellous Bone, DBX Demineralized Bone Matrix and the Procure Bone Marrow Aspiration Kit.
3. Zimmer Biomet (Warsaw, Ind.). Zimmer Spine offers a line of synthetic bone void fillers and allograft demineralized bone matrix products for use in spine surgery. It's CopiOs Bone Void Filler provides a moderately acidic environment which promotes solubility of osteoinductive growth factors such as bone morphogenic proteins.
4. NuVasive (San Diego). NuVasive's biologics portfolio includes procedurally integrated allogeneic bone graft substitutes and extenders, as well as ceramic bone graft substitutes designed to promote bone fusion.
5. Stryker (Kalamazoo, Mich.). Stryker offers biomaterial solutions for open, less invasive and minimally invasive spinal procedures. Its offerings consist of traditional and proprietary spinal allografts, demineralized bone matrix products and a viable bone matrix.
6. Orthofix (Lewisville, Texas.). Orthofix offers allograft products for the treatment of musculoskeletal deficits. Its AlloQuent structural allograft is designed for easy insertion during cervical or lumbar procedures.
7. K2M (Leesburg, Va.). K2M is the largest privately held spinal device company. It offers several Vesuvius osteobiologic offerings, as well as Venado bone graft systems and Vikos allograft systems.
8. Wright Medical Technology (Memphis, Tenn.). Wright Medical is a global medical device company focused on extremities and biologics. Wright offers allograft wedges, amniotic tissue platforms, a core decompression kit, DBM injectables and chip mixes, recombinant growth factor technology and more; it has several biologic products that can be combined with bone marrow aspirate.
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