A titanium skull implant with a rough nanosurface texture demonstrated faster and greater neovascularization than smooth implants at 42 days post-implantation, according to a study in Nature Communications Biology.
The researchers observed over three times more bone formation around the implant with a rough nanosurface in an animal model.
New blood vessels developed proximal to the implant, and the vascular network matured more quickly in the presence of an implant nanosurface.
"The ability for blood vessels to form around an implant is a key factor in its successful tissue integration," said Niloufar Khosravi, the study's first author. "Indeed, neovascularization is vital for tissue healing and regeneration around the implant."
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