The roughened titanium alloy surface of a spinal interbody fusion implant may enhance bone formation, implant stability and fusion compared to smooth titanium, according to a preclinical trial from Researchers at Virginia Commonwealth University School of Engineering. Many other devices focus on the bone growth factors in a device and neglect the blood vessel factors. The study compared production of growth factors with bone and blood vessel formation on the smooth and rough surfaces. They found the rough titanium alloy increased production of growth factors by nearly 100 percent.
The full study can be found in The Spine Journal.
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