Here are 10 of the biggest transactions in the orthopedic and spine device company space over 2017 and the early months of 2018. The transactions were large in terms of value and/or how they will shape industry development in the future.
Integra LifeSciences acquired Johnson & Johnson's Codman Neurosurgery for around $1.05 billion in October.
Stryker acquired Canadian imaging company Novadaq Technologies for $701 million last year.
Smith & Nephew acquired Rotation Medical, a tissue regeneration developer, for $210 million in December.
Orthofix acquired Spinal Kinetics for around $105 million in March.
Stryker acquired shares of Vexim for $97 million in October 2017.
Wright Medical acquired Imascap, a software-based solutions developer for preoperative planning of shoulder replacement surgery, for about $88.8 million in cash and ordinary shares, in December 2017.
Medtronic completed its $40 million investment in Mazor Robotics to partner with the company on future innovation and assume exclusive global spine market commercial responsibility for the Mazor X Surgical Assurance Platform and accessories.
Alphatec acquired SafeOp Surgical, a privately held advanced neuromonitoring technology provider, for more than $18 million.
RTI Surgical acquired Zyga Technology in January. The terms of the agreement were not disclosed, but Zyga brought in around $4 million in annual revenue prior to the acquisition.
DePuy Synthes, a Johnson & Johnson subsidiary, acquired Innovative Surgical Solutions, a nerve localization technology company known as Sentio, for an undisclosed amount.