Total cervical disc replacement performed using Centinel Spine's ProDisc Vivo significantly improved clinical outcomes, according to a study in Spine.
Six things to know:
1. Previous generations of the ProDisc artificial cervical disc replacement generated high primary stability due to keel-based designs with opening of the anterior cortex during implantation, leading to high rates of heterotopic ossifications.
2. The study comprised 55 patients who received a single-level treatment with the ProDisc Vivo cTDR between C3/4 and C6/7, with a two-year follow-up rate of 78 percent.
3. Clinical outcome scores, including the Neck Disability Index, Visual Analogue Scale and arm and neck pain self-assessment questionnaires, improved significantly.
4. The range of motion of the index-segment did not significantly change.
5. The study authors observed three implant-related complications, with two implant dislocations anteriorly and one low-grade infection.
6. The ProDisc Vivo cTDR's less invasive implantation mechanism with lower primary stability may account for a higher dislocation rate than the keel-based previous ProDisc C generation, the study authors concluded.